Tid: 10 april 2006 kl 1515-1600
Plats : Seminarierummet 3733, Institutionen för matematik, KTH, Lindstedts väg 25, plan 7. Karta!
Föredragshållare: Robert Szulkin
Titel: Analysing transmission of cancer from blood donors to recipients using family methods. (Examensarbete)
Sammanfattning: The question if cancer can be transmitted through blood transfusions has been discussed in transfusion medicine for a long time. By defining blood recipients as children and donors as parents this thesis approaches the research question as a "family problem", and adapts methods that are used in studies of family data. The analysed material comes from a database, SCANDAT, which contains data on all blood donors and recipients that have been registered in Sweden (since 1968) and Denmark (since 1983). Statistical tools used are mostly Survival analysis models, i.e. different variants of the Cox proportional hazards regression model. Results from the analysis agree well with simpler epidemiological analysis, and indicate that there is no signifcant risk of transmission of cancer through blood transfusion.