*Tid:* **4 april 2011 kl 15.15-16.00.**
**Seminarierummet 3721**, Institutionen för
matematik, KTH, Lindstedts väg 25.
Karta!
*Föredragshållare:*
**
Lars A. Carlsson, AstraZeneca R&D, Mölndal.
**
**Titel:**
Computational Toxicology at AstraZeneca
**Abstract**
This presentation
will give a short overview of the Drug Discovery process and some of its
pitfalls. In particular we will cover attrition due to safety and explain what
efforts are put in to detecting compounds with liabilities at an early stage. We
will look at the problems at hand within Computational Toxicology and see what
sort of statistical modeling methods that is being used. Computational methods
are getting more and more attention within the pharmaceutical industry, more
or less anything goes as long as problems are solved at a low cost compared to
traditional experiments. Part of the intentions with this presentation is to
see if there are areas where improvements can be done quite easily through
collaborations with mathematicians.
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